More Information about COMBO 41 #2

Information about Conjugated Linoleic Acid (Active Ingredient in COMBO 41 #2)

The Origin of Conjugated Linoleic Acid (CLA):

CLA is a naturally occurring fatty acid found primarily in milk, beef and dairy products such as butter, yogurt and various cheeses.  Traces of CLA can also be found in lamb, veal, turkey, chicken and pork.

Ruminant animals (such as cows) have a special digestive system that converts linoleic acid into CLA, which humans then receive by eating beef and dairy foods.  Changes during the past 30 years in how cattle are raised (grain-fed vs. grass-fed), combined with the market trend toward low-fat dairy, have drastically reduced the amount of CLA humans acquire through diet.  As a result, most of us are not receiving the health benefits CLA offers.

Formation of CLA:

Scientists have utilized a confidential and proprietary process to convert the linoleic acid of safflower oil, a pure and natural vegetable oil, into CLA.  The unique processing for this CLA optimizes its two active isomers to yield a safe, efficient, natural product.

CLA and Body Weight Management:

The prevalence of overweight people worldwide represents a growing threat to the health of the population (American Heart Association).  It is estimated that 63% of the American population is overweight and way over one billion adults worldwide are overweight.  It is no secret that obesity is now a major health concern for our children also.

There is good news in that the health benefits of CLA on body composition appear to be attributed to the two active isomers.  Research indicates that CLA may help reduce body fat while maintaining or increasing lean body mass.  Long term and short term studies have concluded that the addition of CLA to ones diet may reduce body fat by 9% in a time span of one year, without exercise and may reduce body fat by 20%, with exercise three times per week, in the same time span.

Scientific knowledge to date indicates that CLA has two main sites of action

1.  Adipocyte-site where fat is stored

2.  Skeletal muscle cells - principle site where fat is burned for energy.

Based on the studies of these two sites it has been proposed that CLA may decrease body fat mass by:

• decreasing the amount of fat that is stored after eating*
• increasing the rate of fat breakdown in fat cells*
• increasing the rate of fat  metabolism*
• decreasing the total number of fat cells*

Together, these four actions may lead to a decrease in number and size of the sites where fat is stored, which consequently may result in body fat mass decrease.

Safety and Long Term Use:

In long-term studies, subjects consuming CLA reported no adverse affects associated with taking CLA.